Establishment of an expression vector of ngr - specific sirna 筛选及其表达载体构建
2.
The expression of nogo - a and ngr in the brain of senile rat 在老年大鼠脑组织中的表达分布
3.
Nogo - 66 receptor , ngr , cloned in 2001 , is a leucine - rich - repeat glycophosphatidylinositol - anchored membrane protein which mediates nogo - 66 inhibition of axonal outgrowth . both the long acidic amino - terminal domain and the nogo - 66 fragment have strong neurite growth inhibitory activity suggest that nogo - a has at least two inhibitory domains . northern blot , in situ hybridization , western blot and immunocytochemistry analyses show that in addition to oligodendrocytes , nogo - a mrna and nogo - a protein are also expressed in neurons in developing and adult brain and spinal cord , nogo - a is also found in peripheral organs such as heart and testis Northernblot 、原位杂交、 westernblot和免疫组化结果证明： nogo amrna和nogo蛋白除了在cns的寡突胶质细胞中表达，还表达于发育阶段和成年的脑、脊髓和外周神经节的某些神经元中，在外周组织如睾丸和心脏也有表达； nogoe在cns和pns以及多种外周组织中有广泛分布； nogo （除表达于脑和心脏外，在骨骼肌中有较高表达。
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